Grape Seed Extract (formerly O.P.C.-100)


Optimally absorbed grape seed extract formulated to support blood vessel strength and eye health*

Thorne’s Grape Seed Extract is a grape seed phytosome which helps inhibit oxidative damage, protect blood vessels and eye health, and have been shown to reduce swelling and bruising after injury. *

Only 1 left in stock (can be backordered)


The primary constituents of Thorne’s grape seed extract are oligomeric proanthocyanidins (OPCs). OPCs have strong free-radical scavenging (antioxidant) ability, resulting in inhibition of oxidative damage and protection of blood vessels and other tissues. * OPCs have been shown to protect vascular endothelial cells from oxidative damage and appear to strengthen the resistance of cell membranes to injury and impairment. * OPCs also can bind copper and iron, thereby reducing their oxidative effects. * Grape Seed Extract contains Leucoselect Phytosome®, which have demonstrated in studies to reduce the oxidation of LDL-cholesterol in heavy smokers and decrease oxidative stress in diabetics and in healthy individuals after a fatty meal. *

Evidence suggests OPCs enhance the cross-linkage of collagen in skin and other connective tissues. * OPCs have also been shown to decrease capillary permeability, which can be manifest as decreased bruising. * For example, clinical studies demonstrate reduced swelling and improved resolution of sports injuries in athletes who were given OPCs prior to a sporting event. *

A clinical study of 10 healthy volunteers analysing the effect of OPC supplementation on biomarkers of oxidative stress found significantly increased levels of the antioxidant alpha-tocopherol in red blood cell membranes. *

In a randomized human trial, young healthy volunteers received 300 mg of Leucoselect phytosome daily or a placebo. Antioxidant activity was measured at multiple time-points during days one and five. Within 30 minutes after administration on day one, the antioxidant activity measured by “total radical-trapping antioxidant parameter” (TRAP) was significantly elevated compared to placebo. *


This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Grape Seed Extract contains grape seed phytosome – a plant extract complexed with phospholipids, which are derived from soy. Phospholipids contain no soy protein. There are no other soy-based ingredients in Grape Seed Extract.


If pregnant, consult your health professional before using this product.

Additional information

Weight .4 kg
Dimensions 5 × 5 × 9 cm
Thorne - OPC 100 Grape Seed Extract
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